Repo: https://github.com/currentspace/http3 npm: https://www.npmjs.com/package/@currentspace/http3
It’s a native package around Rust/quiche. It supports both client and server APIs, I'm using it in a couple of projects: creating raw QUIC streams, datagrams, custom ALPN, session behavior, and HTTP/3 client work from Node.
I've tried to be very safe in the native code, written in rust, with proofs around the parts I was most concerned about getting wrong. I have it hosting a couple of sites as HTTP3 endpoints and found it working well.